Guideline levels for PFOA and PFOS in drinking water: the role of scientific uncertainty, risk assessment decisions, and social factors

Journal of Exposure Science & Environmental Epidemiology (Springer) | January 8th, 2019

Communities across the U.S. are discovering drinking water contaminated by perfluoroalkyl and polyfluoroalkyl substances (PFAS) and determining appropriate actions. Ther

Communities across the U.S. are discovering drinking water contaminated by perfluoroalkyl and polyfluoroalkyl substances (PFAS) and determining appropriate actions. There are currently no federal PFAS drinking water standards despite widespread drinking water contamination, ubiquitous population-level exposure, and toxicological and epidemiological evidence of adverse health effects. Absent federal PFAS standards, multiple U.S. states have developed their own healthbased water guideline levels to guide decisions about contaminated site cleanup and drinking water surveillance and treatment. We examined perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) water guideline levels developed by the U.S. Environmental Protection Agency (EPA) and state agencies to protect people drinking the water, and summarized how and why these levels differ. We referenced documents and tables released in June 2018 by the Interstate Technology and Regulatory Council (ITRC) to identify states that have drinking water and groundwater guideline levels for PFOA and/or PFOS that differ from EPA’s health advisories (HAs). We also gathered assessment documents from state websites and contacted state environmental and health agencies to identify and confirm current guidelines. Seven states have developed their own water guideline levels for PFOA and/or PFOS ranging from 13 to 1000 ng/L, compared to EPA’s HA of 70 ng/L for both compounds individually or combined. We find that the development of PFAS guideline levels via exposure and hazard assessment decisions is influenced by multiple scientific, technical, and social factors, including managing scientific uncertainty, technical decisions and capacity, and social, political, and economic influences from involved stakeholders. Assessments by multiple states and academic scientists suggest that EPA’s HA is not sufficiently protective. The ability of states to develop their own guideline levels and standards provides diverse risk assessment approaches as models for other state and federal regulators, while a sufficiently protective, scientifically sound, and enforceable federal standard would provide more consistent protection.

Gut Contents Analysis of Four Fish Species Collected in the San Leandro Bay RMP PCB Study in August 2016

San Francisco Estuary Institute (SFEI) | November 7th, 2018

In support of PCB modeling for San Leandro Bay, a Priority Margin Unit (PMU) for PCB load reduction in the estuary, fish samples of four species (topsmelt, shiner perch,

In support of PCB modeling for San Leandro Bay, a Priority Margin Unit (PMU) for PCB load reduction in the estuary, fish samples of four species (topsmelt, shiner perch, white croaker, and northern anchovy ) were obtained in August 2016 for both tissue analysis and examination of gut contents. The bay was sampled at eight locations, with a repeated sampling at one location (Airport Lagoon) for one species (topsmelt). Fish were measured, weighed, and dissected, and their gut contents examined microscopically. Topsmelt (9 samples, 188 specimens) had the greatest variety of food items, with gammarid amphipods and chain diatoms predominating. Some topsmelt, especially larger individuals, consumed macroalgae as a major dietary component. Two samples at two sites for shiner perch (20 fish each) had contents composed of close to 50% gammarids at both sites, but differed in proportions of bivalves and polychaetes among the important food items. The one sample of white croaker had consumed mostly gammarids, with fish and polychaetes ranking next in importance. A single sample of northern anchovy (20 fish analyzed) differed radically from the other species in consuming mainly a diatom that appears to have been filtered from the water column. Trace amounts of plastic fiber were seen in all species except shiner perch. All exposure to sediment appeared to have occurred in the top 2 cm of the sediment column, or as contact with flocculent material on plants or hard substrates, or even in the water column, as some fine sand grains were seen in all fish, even anchovy. There was no conclusive evidence of site-specific foraging (site fidelity). The best spatial coverage was for topsmelt, and these fish appear to have fed opportunistically, with some evidence for having fed outside San Leandro Bay.

Hacienda Avenue Bio-Infiltration Basins

San Francisco Estuary Institute (SFEI) | July 1st, 2016

Handbook for Developing Watershed Plans to Restore and Protect Our Waters

U.S. Environmental Protection Agency (EPA) | March 20th, 2008

This handbook provides information on developing and implementing watershed management plans that help to restore and protect water quality. A watershed is the area of la

This handbook provides information on developing and implementing watershed management plans that help to restore and protect water quality. A watershed is the area of land that contributes runoff to a lake, river, stream, wetland, estuary, or bay. A watershed management plan defines and addresses existing or future water quality problems from both point sources and nonpoint sources of pollutants. Experience over the past decade has shown that effective watershed management includes active participation from stakeholders, analysis and quantification of the specific causes and sources of water quality problems, identification of measurable water quality goals, and implementation of specific actions needed to  solve those problems. This handbook is intended to serve as the basis for developing and implementing watershed plans to meet water quality standards and protect water resources. Although watershed plans are useful for all watersheds to protect and restore water resources, as well as to meet other community resource goals, they are critical for impaired or threatened waterbodies. The most recent national water quality assessment reported that 40 to 50 percent of the nation’s assessed waterbodies are impaired or threatened. 3/20This handbook is designed to provide a framework to help you develop a scientifically defensible plan that will lead to measurable results and an overall improvement in the water quality and watershed conditions that are important to your community.

Hazard: The Future of the Salton Sea With No Restoration Project

Pacific Institute | May 1st, 2006

The Salton Sea lies on the brink of catastrophic change. The amount of water flowing into the Sea in the next twenty years will decrease by more than 40%, causing

The Salton Sea lies on the brink of catastrophic change. The amount of water flowing into the Sea in the next twenty years will decrease by more than 40%, causing its surface elevation to drop by more than 20 feet, rapidly shrinking its volume by more than 60%, tripling its salinity, and exposing more than 100 square miles of dusty lakebed to the desert’s blowing winds. These changes will cause four major impacts: Human health in the Imperial and Coachella valleys – currently home to more than 400,000 people and growing quickly – will be harmed by the estimated 33% increase in the amount of fine windblown dust in the basin. The Imperial Valley already suffers from the highest childhood asthma hospitalization rate in the state; the growing number of retirees living in both valleys are especially susceptible to poor air quality. Air quality in these two valleys – which already fails to meet state and federal air quality standards – would get much worse, increasing the cost of bringing these areas into compliance. Air quality-related litigation and state liability will increase. California has assumed ultimate responsibility for managing only those lands exposed due to a recent set of water transfers, constituting about half of the estimated 134 square miles exposed in 30 years. Responsibility for managing any dust blowing off the other 60 or so square miles will rest with the individual property owner. However, there is no clear way to determine which lands will be exposed due to the water transfers and which will be exposed due to other actions. Total air quality management costs at Owens Lake have exceeded $400 million. Costs at the Salton Sea could be higher. Many – if not most – of the hundreds of thousands of birds that currently use the Sea will lose their roosting and breeding habitats and their sources of food. The Sea’s fish will be almost entirely gone within a dozen years. Those birds that remain will suffer from disease and the reproductive deformities and failures that plagued the Kesterson National Wildlife Refuge twenty years ago. Some of the endangered and threatened species that use the Sea may be able to find other habitats, but others could suffer significant population losses. The tremendous scale of the Sea adds to its complexity, and the difficulty of finding a viable solution. The Sea currently runs almost 35 miles long, and 15 miles at its widest point, covering about 365 square miles. It has the largest surface area of any lake in California, yet is barely 50 feet at its deepest point. The Sea is 1/3 saltier than the ocean, and, fed by the fertilizers running off of neighboring fields, sustains incredible levels of biological productivity. Until recently, the amount of water entering the Sea was roughly balanced by the amount of water evaporating from its broad surface. Stabilizing the Sea at its current salinity would require the removal of more than four million tons of salt each year, assuming flows to the Sea do not change. But they will change. Under a set of agreements signed in 2003, the Imperial Valley has begun to transfer water to San Diego County, ultimately reducing flows to the Salton Sea. Other actions, including actions in Mexico, will also reduce the amount of water flowing to the Sea, by 45% or more in the next 30-40 years. These changes will dramatically decrease the size of the Salton Sea and the quality of its water. In September, 2003, the California legislature passed a set of laws that implement the 2003 water agreements and provide a 15-year reprieve for the Sea. The legislation offers the prospect of more than $300 million of restoration funds, but it does not guarantee a long-term restoration project for the Salton Sea. California’s Resources Agency will submit a Salton Sea Ecosystem Restoration Plan and related documents to the state legislature by December 31, 2006. The cost of any long-term restoration plan will almost certainly exceed a billion dollars. Although various private-public partnerships have been suggested, funding and implementation of any restoration plan is far from certain, especially given the lack of consensus on a preferred alternative.

Hazy Futures: Projecting the local impacts of global warming is a stubborn challenge. But cities need answers fast

American Association for the Advancement of Science (AAAS) | June 5th, 2025

A wastewater treatment plant isn’t top on everyone’s sightseeing itinerary. But on a cloudless, breezy day in April, Agmed Weber, operations manager for the Walnut Cr

A wastewater treatment plant isn’t top on everyone’s sightseeing itinerary. But on a cloudless, breezy day in April, Agmed Weber, operations manager for the Walnut Creek plant—which handles more than half of the sewage here in Texas’s booming capital city—is an enthusiastic tour guide. He marvels at the foresight of those who built the jumbo plant a half-century ago, when Austin was a third of its current size. “They were really thinking about the future,” he says. Weber feels a similar pressure—to prepare for not only continued population growth, but also a hotter future. Austin is “in a tight space where we need to think ahead,” he says.

Healthy, Fair, and Profitable: A Win-Win Pesticide Policy

Pacific Institute | January 1st, 2002

A new report released by the Pacific Institute and the California Green Scissors project makes the case for changing the way pesticides are regulated in California. Acc

A new report released by the Pacific Institute and the California Green Scissors project makes the case for changing the way pesticides are regulated in California. According to the report, if California significantly increased its funding for sustainable agriculture — instead of just spending money to regulate pesticide usage — we could aid California farmers, improve the public health and save millions of dollars in associated costs.

Heavily polluted Tijuana River drives regional air quality crisis

American Association for the Advancement of Science (AAAS) | August 28th, 2025

Intense industrial and urban wastewater pollution has plagued the Tijuana River for decades, causing long-term closure of neighboring beaches. Rico et al. showed that sur

Intense industrial and urban wastewater pollution has plagued the Tijuana River for decades, causing long-term closure of neighboring beaches. Rico et al. showed that surging wastewater flows in the summer of 2024 enhanced water-to-air hydrogen sulfide (H2S) transfer at a turbulent hotspot, leading to nighttime atmospheric H2S peaks thousands of times greater than typical urban levels. This example makes it clear that poor water quality can drastically affect air quality—an observation with important implications for global waterways.

Helium isotope studies in the Mojave Desert, California: implications for groundwater chronology and regional seismicity

Chemical Geology (Elsevier) | November 7th, 2003

Hexavalent Chromium Maximum Contaminant Level (MCL) Standardized Regulatory Impact Assessment (SRIA)

California State Water Resources Control Board (SWRCB) | May 4th, 2023

The Division of Drinking Water (DDW) of the State Water Resources Control Board (State Water Board) is responsible for adopting drinking water standards. Primary drinking

The Division of Drinking Water (DDW) of the State Water Resources Control Board (State Water Board) is responsible for adopting drinking water standards. Primary drinking water standards, as defined in section 116275 of the California Safe Drinking Water Act (Health & Safety Code (HSC), div. 104, pt. 12, ch. 4, section 116270 et seq.), must be set in accordance with the requirements of HSC 116365. The purpose of the proposed regulation addressed in this Standardized Regulatory Impact Assessment (SRIA) is to adopt a primary drinking water standard for hexavalent chromium in drinking water consisting of a maximum contaminant level (MCL) and pertinent monitoring and reporting requirements. Consistent with title 1 of the California Code of Regulations (CCR), section 2003(a), the economic impact method used for the assessment was the Regional Input-Output Modeling System (RIMS II) developed by the U.S. Bureau of Economic Analysis (BEA).