Sociodemographic predictors of PFAS exposure among a combined sample of U.S. pregnant women: an Environmental influences on Child Health Outcomes (ECHO) public-use dataset analysis
Jessie A. Gleason, Kristen Lyall, Jerald A. Fagliano, Lucy F. Robinson, Gloria B. Post, Anneclaire J. De Roos | December 15th, 2025
Compared with White mothers, Black mothers had lower levels of PFOA (−23%; 95% CI −29%, −16%), PFOS (−9%; 95% CI −16%, −1%), and PFHxS (−23%; 95% CI −29%, −14%) based on linear analysis, and lower detection of PFOSA, EtFOSAA, PFDoDA, and PFPeA and higher detection of PFBS and PFHxA based on logistic analysis. Compared with White mothers, Asian mothers had higher levels of PFNA ( + 26%; 95% CI 13%, 40%), PFDA ( + 60%, 95% CI 36%, 89%), and PFUnDA (+95%; 95% CI 63%, 134%) based on linear analysis and higher detection of PFPeA based on logistic regression. Greater weekly fish consumption was found to be a significant predictor of PFAS concentrations but did not attenuate associations with Asian race. Compared with non-Hispanic mothers, Hispanic mothers had lower levels of most of PFAS analytes studied. Higher levels of maternal education were associated with increased levels of most PFAS analytes.
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