This special study of the Regional Monitoring Program for Water Quality in San Francisco Bay was conducted to support the Dredged Material Management Office (DMMO) process of evaluating results from bioaccumulation testing performed for routine dredging projects. The goal was to use the current DMMO methodology for selecting Toxicity Reference Values (TRVs) from the US Army Corps of Engineers Environmental Residue-Effects Database (ERED), in order to develop a standard list of TRVs for San Francisco Bay. TRVs are used as a conservative screening tool to efficiently evaluate whether observed invertebrate test organism body burdens could indicate adverse ecological effects on benthic organisms in situ. Currently, there are no published standard TRVs for the Bay, and TRV selection is presently performed on a case-by-case basis during the evaluation of bioaccumulation testing results submitted by individual dredgers. A standard list would promote consistent application of the methodology and improve the efficiency of dredging project evaluations.