This report details plans associated with the annual Regional Monitoring Program for Water Quality in the San Francisco Estuary (RMP) sediment cruise. The Regional Monitoring Program through the Status and Trends conducts routine monitoring of water, sediment and biological tissue. The current study design calls for monitoring of water and bivalves every two years and sediment every four years. Bird egg monitoring (cormorant and terns) is conducted triennially, while sport fish are monitored on a five-year rotation. For 2018, sampling operations will entail dry season sample collection at 27 RMP sediment sampling sites.